Cyclosporine and Echinacea

Supplement–drug interaction evidence from the TruthStack database.

SeverityCRITICAL
Evidence TierModerate
Interaction TypeCONTRAINDICATED
MechanismPHARMACODYNAMIC
Last Reviewed2026-02-15

Summary

Echinacea immunostimulation opposes cyclosporine immunosuppression. Risk of transplant rejection. This is a high-risk combination. Discuss with your prescriber or pharmacist before combining.

API Reference

GET https://api.truthstack.co/v1/check?c1=cyclosporine&c2=echinacea

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.