Cbd and Metformin
Supplement–drug interaction evidence from the TruthStack database.
| Severity | LOW |
|---|---|
| Evidence Tier | Moderate |
| Interaction Type | ANTAGONISTIC |
| Mechanism | PHARMACOKINETIC |
| Last Reviewed | 2026-02-15 |
Summary
CBD does not significantly affect metformin metabolism (renal elimination). However CBD may affect glycemic control independently. Monitor blood glucose. Low interaction risk.
Higher-Concern Contexts
This interaction may be of particular concern in the following contexts:
- renal impairment
API Reference
GET https://api.truthstack.co/v1/check?c1=cbd&c2=metformin
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.