Pyridoxine B6 and SAMe

Supplement–drug interaction evidence from the TruthStack database.

SeverityINFO
Evidence TierModerate
Interaction TypeUNKNOWN
Mechanismpharmacokinetic, physiological
Last Reviewed2026-02-07

Summary

Include B6 25-50mg especially if homocysteine elevated Discuss with your prescriber or pharmacist.

API Reference

GET https://api.truthstack.co/v1/check?c1=pyridoxine_b6&c2=same

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

Cobalamin B12 + SAMe Folate B9 + SAMe Methylene Blue + SAM-E 5-HTP + SAM-E SAM-E + Vitamin B12 SAM-E + Vitamin B9 5 Htp + SAMe Citalopram + Sam-E
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.