Omeprazole and Resveratrol
Supplement–drug interaction evidence from the TruthStack database.
| Severity | MODERATE |
|---|---|
| Evidence Tier | Moderate |
| Interaction Type | SAFETY CONCERN |
| Mechanism | PHARMACOKINETIC |
| Last Reviewed | 2026-02-16 |
Summary
Resveratrol modulates CYP3A4 and other CYP enzymes involved in omeprazole metabolism. Polyphenol-mineral chelation may compound PPI-related nutrient malabsorption with long-term combined use.
API Reference
GET https://api.truthstack.co/v1/check?c1=Omeprazole&c2=Resveratrol
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.