Cinnamon and Metformin

Supplement–drug interaction evidence from the TruthStack database.

SeverityLOW
Evidence TierModerate
Interaction TypePHARMACODYNAMIC RISK
MechanismPHARMACODYNAMIC
Last Reviewed2026-02-15

Summary

Cinnamon may modestly improve insulin sensitivity. Low individual risk but contributes to hypoglycemia stacking with other glucose-lowering supplements. Discuss with your prescriber or pharmacist.

Higher-Concern Contexts

This interaction may be of particular concern in the following contexts:

API Reference

GET https://api.truthstack.co/v1/check?c1=cinnamon&c2=metformin

Open, unauthenticated. Returns JSON. Developer documentation

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What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.