Atorvastatin and Red Yeast Rice

Supplement–drug interaction evidence from the TruthStack database.

SeverityCRITICAL
Evidence TierModerate
Interaction TypeCONTRAINDICATED
MechanismPHARMACODYNAMIC
Last Reviewed2026-02-15

Summary

This is a high-risk combination. Discuss with your prescriber or pharmacist before combining. Red yeast rice contains monacolin K (identical to lovastatin). Combined with atorvastatin equals statin stacking with risk of rhabdomyolysis and acute kidney injury.

Higher-Concern Contexts

This interaction may be of particular concern in the following contexts:

API Reference

GET https://api.truthstack.co/v1/check?c1=atorvastatin&c2=red%20yeast%20rice

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

Cyclosporine + Red Yeast Rice Pravastatin + Red Yeast Rice Red Yeast Rice + Rosuvastatin Red Yeast Rice + Simvastatin Atorvastatin + Bergamot Atorvastatin + Biotin Atorvastatin + Calcium Atorvastatin + CoQ10
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.