Ashwagandha and Holy Basil
Supplement–drug interaction evidence from the TruthStack database.
| Severity | LOW |
|---|---|
| Evidence Tier | Moderate |
| Interaction Type | SYNERGISTIC |
| Mechanism | PHARMACODYNAMIC |
| Last Reviewed | 2026-02-15 |
Summary
Different adaptogenic mechanisms; ashwagandha GABA, holy basil cortisol/COX-2. Rotate or combine for comprehensive adaptogen support
API Reference
GET https://api.truthstack.co/v1/check?c1=Ashwagandha&c2=Holy%20Basil
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.