L-Theanine and Lion'S Mane

Supplement–drug interaction evidence from the TruthStack database.

SeverityLOW
Evidence TierModerate
Interaction TypeSYNERGISTIC
MechanismPHARMACODYNAMIC
Last Reviewed2026-02-15

Summary

L-Theanine dampens glutamate excitability from high NGF stimulation. Pair L-Theanine 200mg with Lion's Mane

API Reference

GET https://api.truthstack.co/v1/check?c1=L-Theanine&c2=Lion's%20Mane

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

Curcumin + Lion'S Mane Green Tea Extract + L-Theanine GABA + L Theanine Alpha-GPC + Lion'S Mane Ashwagandha + Lion'S Mane Lion'S Mane + NAC Lion'S Mane + Zinc Caffeine + L-Theanine
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.