Famotidine and Iron
Supplement–drug interaction evidence from the TruthStack database.
| Severity | MODERATE |
|---|---|
| Evidence Tier | Moderate |
| Interaction Type | SAFETY CONCERN |
| Mechanism | PHARMACOKINETIC |
| Last Reviewed | 2026-02-15 |
Summary
Famotidine reduces stomach acid which is needed for iron absorption. Iron supplementation may be less effective. Consider taking iron on an empty stomach or with vitamin C. Discuss with your prescriber or pharmacist.
API Reference
GET https://api.truthstack.co/v1/check?c1=famotidine&c2=iron
Open, unauthenticated. Returns JSON. Developer documentation
Related Interactions
What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.