Calcium and Vitamin K2

Supplement–drug interaction evidence from the TruthStack database.

SeverityHIGH
Evidence TierModerate
Interaction TypeSYNERGISTIC CRITICAL
Mechanismphysiological
Last Reviewed2026-02-07

Summary

Always include K2 when supplementing calcium, especially with vitamin D

API Reference

GET https://api.truthstack.co/v1/check?c1=calcium&c2=vitamin_k2

Open, unauthenticated. Returns JSON. Developer documentation

Related Interactions

What this page is and is not. TruthStack is an informational reference database that describes published pharmacological findings. It does not provide medical advice, diagnosis, or treatment recommendations. The information on this page reflects flags in our database and should not replace consultation with a qualified healthcare provider. Always discuss supplement-drug combinations with your prescriber or pharmacist.